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We report a case of an acute ST-segment elevation myocardial infarction in a patient with traditional cardiac threat elements utilizing supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this affected person also had polycythemia, probably secondary to high-dose testosterone. The patient underwent profitable percutaneous intervention of the proper coronary artery. Physicians and sufferers ought to be aware of the medical consequences of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996).
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Moreover, a component of endothelial dysfunction has been proposed, which may contribute to irregular vessel reactivity. However, testosterone in physiologic doses could even be helpful in sufferers with angina , have larger ischemic thresholds and improved high quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and will increase coronary blood move in males with established coronary artery disease . Therefore, an interaction of endogenous factors of the patient’s risk profile in addition to the testosterone dosing may be issues of whether opposed occasions occur.